Table 1

Clinical studies of PRP for RC tear

NoYearAuthorStage of diseaseUsageDesignClinical outcomesStructural outcomes
12008EvertsImpingementSurgeryRCTBetterNA
2RandelliRC tearSurgeryCase seriesImprovedNA
32011CastriciniRC tearSurgeryRCTNo differenceNo difference
4JoRC tearSurgeryCase seriesNo differenceNo difference
5RandelliRC tearSurgeryRCTNo difference except for <1 monthNo difference
6BarberRC tearSurgeryRCTNo difference except for RoweBetter
7MarquezRC tearSurgeryRCTNo differenceNo difference
82012GuminaRC tearSurgeryRCTNo differenceBetter
9BergesonRC tearSurgeryRCTNo differenceWorse
10RodeoRC tearSurgeryRCTNo differenceNo difference
11MalavoltaRC tearSurgeryCase seriesImprovedNo difference
122013Ruiz-MoneoRC tearSurgeryRCTNo differenceNo difference
13ScarponeRC tearInjectionCase seriesImprovedImproved
14WeberRC tearSurgeryRCTNo differenceNo difference
15AntunaRC tearSurgeryRCTNo differenceNo difference
16JoRC tearSurgeryRCTNo differenceBetter
17RhaRC tearInjectionRCTBetterNA
18KesikburunRC tearInjectionRCTNo differenceNA
192014CharoussetRC tearSurgeryRCTNo differenceNo difference
20ZumsteinRC tearSurgeryRCTNo differenceNo difference
21MalavoltaRC tearSurgeryRCTNo differenceNo difference
22WertherlRC tearSurgeryCase–controlNo differenceNo difference
232015HakRC tearSurgeryRCTNo differenceNA
24WangRC tearSurgeryRCTNo differenceNo difference
25Von WehrenRC tearInjectionCase–controlBetter in earlyNo difference
26JoRC tearSurgeryRCTNo differenceBetter
27IlhanliRC tearInjectionRCTNo difference except for DASHNA
28CarrTendinopathySurgeryRCTNo differenceNA
292016ZhangRC tearSurgeryRCTNo differenceBetter
30WesnerRC tearInjectionCase seriesBetterBetter
31SayRC tearInjectionCase–controlWorseNA
32ShamsRC tearInjectionRCTBetter at 12 weeksNo difference
33PandeyRC tearSurgeryRCTBetterBetter in large only
34HoltbyRC tearSurgeryRCTBetter at 1 month in pain reductionNo difference
35FluryRC tearSurgeryRCTNo differenceNo difference
36BarberRC tearSurgeryRCTNo differenceNo difference
37ZumsteinRC tearSurgeryRCTNo differenceNo difference
38D’AmbrosiRC tearSurgeryRCTBetter at 1 month in pain reductionNo difference
39GwinnerRC tearSurgeryRCTNo differenceNo difference
402017SengodanRC tearInjectionCase seriesImprovedImproved
41LadermannRC tearInjectionCase seriesImprovedImproved
42KimRC tearInjectionCase seriesBetterNo difference
43EbertRC tearSurgeryRCTNo difference except for abduction powerNo difference
  • DASH, Disabilities of the Arm, Shoulder and Hand score; NA, not available; PRP, platelet-rich plasma; RC, rotator cuff; RCT, randomised controlled trial.